Is there a way to...

[ibron]

... make different huds (in cash game) for 2 different sites?
... save different database for different sites (1 for ftp other for other one)? I can choose but it isnt saved.

[WhiteRider]

... make different huds (in cash game) for 2 different sites?

You can't have different stat Groups, but the positions you drag the stats into will be saved separately for each site and table size when you PT-icon -> Save Layout.

... save different database for different sites (1 for ftp other for other one)? I can choose but it isnt saved.

Not yet - this is planned, but shouldn't really be necessary; postgres can handle pretty huge databases.